It does work, it’s just complicated to setup.

In that picture, I’m using KDE applications that are flatpaks for Cosmic Desktop on PopOS with a Kvantum theme. I made a longer post here when I was searching for instructions for how to complete this recently.

After my experience, I don’t really know what the best solution is for setting it up. I guess it would be nice if the major platform applications for like KDE were supported for dark mode by default on the DE. I don’t know, it really bothered me though.

Maybe share a GPU to different users of the same computer who are just using different monitors. This isn’t virtualization, it seems like it’s just workspaces created within workspaces, so it’s maybe capable of managing a workspace per monitor.