Electro Convulsive Therapy - they literally shock your brain at high voltages for 10-15 minutes a few times per session.

In my opinion, its extremely under-studied and over prescribed. It should be a completely last ditch attempt extreme cases of treatment resistant depression.

My wife had several ECT treatments over the last few years and is now a completely different person. Depression is alleviated, but we both agree that cognitively she’s worse off than she was before.

Fuck that shit.